{"repo":"ckoenigs/PharMeBINet","free":true,"listed":false,"github":"https://github.com/ckoenigs/PharMeBINet","clone":"git clone https://github.com/ckoenigs/PharMeBINet.git","description":"Build PharMeBINet from different sources.","language":"Python","stars":22,"topics":["database","graph-database","neo4j"],"license":null,"category":"databases-storage","readme_excerpt":"PharMeBINet: The heterogeneous pharmacological medical biochemical network Heterogeneous biomedical pharmacological databases are important for multiple fields in bioinformatics. The Hetionet database already covers many different entities. Therefore, it was used as the basis for this project. 51 different pharmacological medical and biological databases such as CTD, DrugBank, and ClinVar are parsed and integrated into Neo4j. Afterward, the information is merged into Hetionet. Different mapping methods were used such as external identification systems or name mapping. The resulting open-source Neo4j database PharMeBINet has 8,813,924 different nodes with 80 labels and 60,408,810 relationships with 441 edge types. It is a heterogeneous database containing interconnected information on ADRs, diseases, drugs, genes, gene variations, proteins, and more. Relationships between these entities represent, for example, drug-drug interactions or drug-causes-ADR relations. It has much potential for developing further data analyses including machine learning applications. A web application for accessing the database is free to use for everyone and available at https://pharmebi.net. Additionally, the database is deposited on Zenodo at https://doi.org/10.5281/zenodo.21276722. All data sources are first integrated into a Neo4j database (version 5.26.4). Next, the disparate sources are mapped, aligned, and merged to form PharMeBINet alongside the additional data sources. Finally, the PharMeBI","default_branch":null,"files":null,"tree":[],"storefront":"/r/ckoenigs","claimed":false,"request_supported":{"post":"https://gitbuyer.com/r/ckoenigs/PharMeBINet/request-supported","requests":0},"note":"indexed from public GitHub; nothing is for sale on this page. Clone it from GitHub. Paid listings live at /search."}