{"repo":"GuoBioinfoLab/TCRdb","free":true,"listed":false,"github":"https://github.com/GuoBioinfoLab/TCRdb","clone":"git clone https://github.com/GuoBioinfoLab/TCRdb.git","description":"A database of T-cell receptor sequences","language":"Python","stars":11,"topics":["tcr","tcr-repertoire","database","bioinformatics"],"license":null,"category":"databases-storage","readme_excerpt":"TCRdb(2.0): A comprehensive T-cell receptor sequences database The unique features of TCRdb include: Comprehensive and reliable sequences for TCR repertoire in different samples generated by a strict and uniform pipeline of TCRdb; Powerful search function, allowing users to identify their interested TCR sequences in different conditions; Categorized sample metadata, enabling comparison of TCRs in different sample types; Interactive data visualization charts, describing the TCR repertoire in TCR diversity, length distribution and V-J gene utilization. Newly Update A substantial increase in data volume, with the number of TCR samples growing from 8,265 to 19,701 and the number of TCR sequences expanding from 277 million to about 700 million Construction of the largest TCR reference in healthy samples, which contains 1,888 samples labeled as healthy controls from 40 published studies. New search function, supporting batch search. Redesigned download function Description CATT .smk , MiXCR.smk , IMSEQ.smk : The parameters used for each method. Download.smk ： For data download from NCBI (Deprecated in TCRdb 2.0). QC single/double.smk : For raw data quanlity control. All the pipepines were written in Snakemake. Citing Si-Yi Chen, Tao Yue, Qian Lei, An-Yuan Guo, TCRdb: a comprehensive database for T-cell receptor sequences with powerful search function, Nucleic Acids Research , , gkaa796, https://doi.org/10.1093/nar/gkaa796 Tao Yue, Si-Yi Chen, Wen-Kang Shen, Yu Liao, Qian Lei, An-Yu","default_branch":null,"files":null,"tree":[],"storefront":"/r/GuoBioinfoLab","claimed":false,"request_supported":{"post":"https://gitbuyer.com/r/GuoBioinfoLab/TCRdb/request-supported","requests":0},"note":"indexed from public GitHub; nothing is for sale on this page. Clone it from GitHub. Paid listings live at /search."}